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Case study for understanding MTX resistance in Leishmania
By Bennet Varghese Faculty mentor: Dr. Swati Agrawal 9:00-9:50am, HCC 328 Leishmania is a parasite that causes Leishmaniasis, a neglected tropical disease that has many forms and potentially deadly symptoms. Methotrexate(MTX) is a drug that has been highly effective at treating and stopping Malaria infection by inhibiting the DHFR enzyme in the folate pathway. Since MTX…
