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Endothelial Tube Maintenance in a HUVEC cell Model for Myotonic Dystrophy Type 1
By Grace Holcomb and Jada Gundy Faculty mentor: Dr. Ginny Morriss Myotonic dystrophy type 1 (DM1) is a multi-systemic condition that results in severe muscle weakening and wasting. DM1 is caused by an expanded region of CTG repeats in the 3’ untranslated end of the DMPK gene. Muscles require vasculature to supply nutrients and oxygen…