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Localization of Transgenes for Drosophila Models of Myotonic Dystrophy Type 1
By Andrea Waltrip and Noah Smith Faculty mentor: Dr. Ginny Morriss Myotonic Dystrophy Type 1, DM1, is a multi-systemic disorder that results from expansion of CTG repeats in the DMPK gene in humans. Drosophila melanogaster has been established as a model organism for the study DM1, by the construct of multiple transgenic DM1 lines containing different numbers of CTG…